Collection: IVD‑READY Gold Nanoparticles for Biosensing

NanoBrand IVD‑READY Gold Nanoparticles are engineered for high‑performance in-vitro diagnostics (IVD), providing sensitive and reliable detection of biomolecules across multiple assay formats. This collection is optimized for developers of lateral flow assays (LFAs), ELISA, microfluidics, and advanced biosensor platforms who require consistent optical performance, robust bioconjugation, and regulatory‑ready documentation.

What “IVD‑READY” means

“IVD‑READY” designates NanoBrand Gold Nanoparticles that meet stringent criteria for use in in-vitro diagnostic assays. This includes strict monodispersity (low CoV and PdI), well‑defined size and spherical morphology, reactant‑free formulations, and precisely controlled surface chemistries to support stable, reproducible conjugation to antibodies, proteins, and nucleic acids.

Each IVD‑READY lot is supplied with a detailed Certificate of Analysis (CoA) including lot-specific TEM images, size distribution, UV‑Vis spectra, hydrodynamic diameter, zeta potential, and key QC metrics. This level of characterization simplifies method validation, lot qualification, and documentation from feasibility through verification, validation, and scale‑up.

Why Monodispersity and Purity Matter

High‑quality IVD biosensing depends on nanoparticle consistency. Monodisperse gold nanoparticles deliver uniform optical response and predictable surface behavior, enabling consistent signal intensity, improved sensitivity, and reliable quantitative analysis. High purity minimizes background interference and non‑specific binding, enhancing specificity and reducing assay noise.

Together, these properties are essential for developing reproducible, scalable, and regulatory‑ready diagnostic systems based on gold nanoparticle biosensors.

Engineered for Diagnostic Applications

NanoBrand IVD‑READY Gold Nanoparticles feature controlled size distribution, spherical morphology, and clean surfaces for efficient bioconjugation and stable integration into a wide range of IVD formats, including:

• Lateral flow assays (LFAs) and rapid diagnostic tests
• ELISA and colorimetric immunoassays
• Microfluidic and lab‑on‑chip systems
• Immunoassays and protein detection
• Molecular diagnostics and nucleic acid detection
• Optical and plasmonic biosensor platforms

Available in commonly used sizes and optical densities (OD 20 and OD 50), this collection offers flexibility for both research‑grade assay development and transition to commercial diagnostic manufacturing.

Surface Options for Flexible Conjugation

To support diverse IVD biosensing strategies, IVD‑READY gold nanoparticles are offered with tailored surface chemistries:

• Citrate‑coated gold nanoparticles for rapid, passive adsorption–based conjugation, ideal for screening and early‑stage assay optimization.
• PEG5000‑carboxylate gold nanoparticles for covalent coupling of amine‑containing biomolecules (e.g., antibodies, proteins, oligonucleotides), improving targeting specificity, stability, and performance in complex matrices.

These surface options enable seamless integration into diagnostic workflows while maintaining colloidal stability, low background, and lot‑to‑lot reproducibility. Customized surface coatings are available on request.

Available IVD‑READY Gold Nanoparticle Products